国家级

• 国家重点研发计划项目：2017YFA0504100，细胞编程与重编程相关蛋白质机器研究
• 国家重点研发计划课题：2022YFF0903303， 产业大脑的三元空间虚实协同脑机服务技术研究
• 国家重点研发计划课题：2022YFA1104603， 含多级血管网的大尺度复杂组织3D打印与功能重建研究
• 国家重点研发计划课题：2018YFB0204000，国家高性能计算环境服务化机制与支撑体系研究（二期）
• 国家重点研发计划任务：2017YFC1200205，微生物多组学生物信息新算法研究与平台构建
• 国家自然科学基金重点项目：92068201，c-JUN介导心肌细胞命运决定的机制研究
• 国家自然科学基金面上项目：61972358，移动边缘云中高效资源组合及存储分配的关键技术研究
• 长三角科技创新共同体联合攻关项目：2022CSJGG1000，基于人工智能的国产化超大规模生命组学高性能计算分析系统研发

省部级

• 浙江省“尖兵”“领雁”研发攻关项目：2025C01115，面向重大疾病的计算生物学关键技术及应用
• 浙江省“尖兵”“领雁”研发攻关项目：2023C03195，新一代“浙里急救”平台关键技术研究及应用示范
• 浙江省“尖兵”“领雁”研发攻关项目：2023C01044，面向元宇宙的数字虚拟内容人机协作制作平台
• 浙江省“尖兵”“领雁”研发攻关项目：2023C03044，智慧中医环境下西黄丸在乳腺癌新辅助化疗中应用的新技术研究及推广
• 浙江省“尖兵”“领雁”研发攻关项目：2022C03087，边云链协同环境下新生儿先天性心脏病筛查与诊断新技术研究及应用
• 浙江省“尖兵”“领雁”研发攻关项目：2022C03043，基于异质多模态数据融合的卒中后认知功能障碍智能诊疗技术研究与应用示范
• 浙江省重点研发项目：2021C03145，面向全生命周期生物样本资源的云链融合共享平台及应用示范
• 浙江省重点研发项目：2021C04044，基于海量VR数据的人工智能教学系统及关键技术研究
• 浙江省重点研发项目：2020C03071，面向脑血管病精准医学的人工智能技术与系统开发
• 浙江省重点研发项目：2020C03057，自噬通路关键激酶ULK1作为肝细胞潜在治疗靶点及药物先导物研究
• 浙江省重点软科学研究项目：2022C25058，生命健康科创高地监测评估和对策研究
• 浙江省重点软科学研究项目：2021C25051，加快推进生物技术创新发展 打造生命健康科创高地对策研究
• 浙江省基础公益研究项目：LQ20F020010，面向物联网的密文检索技术研究
• 浙江省基础公益研究计划：LGF20H180004，基于间充质干细胞构建用于肝毒性检测的肝脏类器官及其评价体系研究

获奖

• 大数据安全存储系统关键技术与产业化，浙江省科技进步奖二等奖，2017
• 多源异构医疗大数据融合挖掘与隐私保护技术研究及应用，中国产学研合作创新与促进奖产学研合作创新成果奖二等奖，2022
• 健康医疗大数据挖掘与隐私保护关键技术及应用，中国发明协会发明创业奖创新奖二等奖，2023
• 基于边云链数据协同的先心病辅助筛诊技术及应用，中国发明协会发明创业奖成果奖二等奖，2024
• 基于AI的国产化多源异构生物医学大数据融合分析及应用，中国商业联合会服务业科技创新奖一等奖，2025

代表性论文

○  "Service-Oriented Secure Federated Learning via Blockchain Orchestration and Byzantine-Resilient Consensus," IEEE Transactions on Services Computing, 2026.
○  "Astilbin from Smilax glabra Roxb. attenuates high-fat/high-sucrose diet-induced dyslipidemia in zebrafish: An integrated multi-omics analysis," Food Bioscience, 2026.
○  "Towards Optimal Speculative Decoding: A Comprehensive Survey on Optimizations and Future Directions," ACM Computing Surveys, 2026.
○  "Self-assembled chamber-like cardiac organoids for modeling cardiac chamber formation and cardiotoxicity assessment," Nature Communications, 2026.
○  "One-Shot Federated Learning With Lightweight Intermediate Models in Wireless Sensor Network Setting," IEEE Internet of Things Journal, 2026.
○  "Machine learning-assisted Mn-N-C nanozyme colorimetric sensor array for trace-level detection of biogenic amines in meat," Food Chemistry, 2026.
○  "Hierarchical text classification utilizing logic rule constraints through message passing," Expert Systems with Applications, 2026.
○  "Unraveling the characteristic structures of Cuscuta chinensis Lam. polysaccharides and its inhibitory effects on non-alcoholic fatty liver disease," International Journal of Biological Macromolecules, 2025.
○  "Two-layer tensor decomposition for temporal kge graph completion," Expert Systems with Applications, 2025.
○  "Sequences and nodes: Probability-guided contrastive learning for hierarchical text classification," Knowledge-Based Systems, 2025.
○  "KA²SE: Key-Aggregation Authorized Searchable Encryption Scheme for Data Sharing in Wireless Sensor Networks," IEEE Transactions on Services Computing, 2025.
○  "Human epicardial organoids from pluripotent stem cells resemble fetal stage with potential cardiomyocyte- transdifferentiation," Cell & Bioscience, 2025.
○  "EvidenceMap: Learning evidence analysis to unleash the power of small language models for biomedical question answering," Artificial Intelligence in Medicine, 2025.
○  "Blockchain-Based Verifiable Decentralized Identity for Intelligent Flexible Manufacturing," IEEE Internet of Things Journal, 2025.
○  "An improved two-stage zero-shot relation triplet extraction model with hybrid cross-entropy loss and discriminative reranking," Expert Systems with Applications, 2025.
○  "A versatile chitosan hydrogel crosslinked by boronated diol drug conjugates as anti-tumor immune stimulator for hepatocellular carcinoma treatment," Carbohydrate Polymers, 2025.
○  "Mechanochemistry-Assisted Fabrication of (Carboxymethyl)cellulose Mediated by Minute Surface-Confined Water," ACS Sustainable Chemistry & Engineering, 2024.
○  "Complex expressional characterizations learning based on block decomposition for temporal knowledge graph completion," Knowledge-Based Systems, 2024.
○  "Antibiotic altered liver damage induced by aflatoxin B1 exposure in mice by modulating the gut microbiotamicrobiota," Environmental Pollution, 2024.
○  "Time-Aware Smart City Services Based on QoS Prediction: A Contrastive Learning Approach," IEEE Internet of Things Journal, 2023.
○  "A Secure Dynamic Mix Zone Pseudonym Changing Scheme Based on Traffic Context Prediction," IEEE Transactions on Intelligent Transportation Systems, 2022.
○  "Self-Attention Mechanism Enhanced User Interests Modeling for Personalized Recommendation Services in Cyber-Physical-Social Systems," IEEE Transactions on Network Science and Engineering, 2022.
○  "Astilbin from Smilax glabra Roxb. alleviates high-fat diet-induced metabolic dysfunction," Food & Function, 2022.
○  "Diet composition affects long-term zearalenone exposure on the gut–blood–liver axis metabolic dysfunction in mice," Ecotoxicology and Environmental Safety, 2022.
○  "基于非协作博弈的边缘分布式缓存方案," 软件学报, 2022.
○  "A blockchain-based fine-grained data sharing scheme for e-healthcare system," Journal of Systems Architecture, 2022.
○  "Secure Fine-Grained Encrypted Keyword Search for E-Healthcare Cloud," IEEE Transactions on Dependable and Secure Computing, 2021.
○  "EDM-Fuzzy: An Euclidean Distance Based Multiscale Fuzzy Entropy Technology for Diagnosing Faults of Industrial Systems," IEEE Transactions on Industrial Informatics, 2021.
○  "A Hybrid Neural Network Architecture to Predict Online Advertising Click-Through Rate Behaviors in Social Networks," IEEE Transactions on Network Science and Engineering, 2021.
○  "Symmetry-aided clustering blind detectionin spatial modulation systems," IEEE Transactions on Vehicular Technology, 2021.
○  "Construction of a lncRNA/pseudogene-hsa-miR-30d-5p-GJA1 regulatory network related to metastasis of pancreatic cancer," Genomics, 2021.
○  "SDABS: A Flexible and Efficient Multi-Authority Hybrid Attribute-Based Signature Scheme in Edge Environment," IEEE Transactions on Intelligent Transportation Systems, 2021.
○  "Energy-efficient scans by weaving indexes into the storage layout in computing platforms for internet of things," IEEE Transactions on Green Communications and Networking, 2021.
○  "Growth factors-based beneficial effects of platelet lysate on umbilical cord-derived stem cells and their synergistic use in osteoarthritis treatment," Cell Death & Disease, 2020.
○  "CircAGFG1 drives metastasis and stemness in colorectal cancer by modulating YY1/CTNNB1," Cell Death & Disease, 2020.
○  "An Industrial Analysis Technology About Occupational Adaptability and Association Rules in Social Networks," IEEE Transactions on Industrial Informatics, 2020.
○  "Multi-value-Independent Ciphertext Policy Attribute Based Encryption with Fast Keyword Search," IEEE Transactions on Services Computing, 2020.
○  "Genome-wide DNA methylation analysis reveals significant impact of long-term ambient air pollution exposure on biological functions related to mitochondria and immune response," Environmental Pollution, 2020.